The Danish Center for Ultrahigh-Field NMR Spectroscopy is a national facility that offers unique infrastructure and expertise in the field of solid-state NMR, liquid-state NMR, and micro-MRI to study biological problems, polymers, and materials.
Specifically, the competences and technologies include
NMR method developments – insoluble proteins – intrinsically disordered proteins – protein-lipid interactions and lipidomics – NMR simulations
The laboratory hosts 950, 700, 600, 500, 400, 300, and 43 MHz spectrometers equipped for a broad range of experiments, including ultrafast MAS NMR, high-field cryo probe for liquid-state NMR, flatcoil probes for oriented membrane proteins, and high-field micro-MRI.
The NMR team is specialised NMR studies of intrinsically disordered proteins, protein dynamics, protein-lipid interactions, and lipidomics, with substantial focus on NMR method development to exploit structural and dynamic features of such biological systems. In addition, the in-house developed NMR simulation software SIMPSON will be established as a “virtual NMR spectrometer”, e.g. for exploratory feasibility studies and modelling of advanced NMR experiments.
The Center is hosted by the Interdisciplinary Nanoscience Center (iNANO) at Aarhus University, as part of a comprehensive state-of-the-art platform for nanoscience characterization (STM, AFM, (cryo)-EM, SAXS, single-molecule FRET, etc.). This setup strongly encourages and promotes interdisciplinary research collaborations for the benefit of both internal and external users of the Center.
Further information is available at: http://nmr.au.dk